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Tips for using Fluorouracil on fingers and hands?

I have used Fluorouracil every year for the past 4 yrs each January, but do not use it on my hands due to frequent hand washing. This year with Covid, I am washing them even more. Can using Fluorouracil only at bedtime work instead?

  1. @SusieQ21...You raise a really great question. I haven't used the cream on my hands, but I do know other users who have. While I can't say for sure how many times a day they used the cream, I do know that many doctors prescribe it for use just once daily. There are many variations in prescribed times and dosage from one patient to the next.

    I would guess that if you are going to try to use the cream once daily, your doctor would suggest extending the length of time you will use it. For instance, if you generally treat twice a day for two weeks, your doctor might ask you to use the cream nightly for four weeks. All of that would depend on the severity of your actinic keratosis.

    I suggest, as with any dosage questions, that you contact your prescribing physician and tell him/her about your concerns. Your doctor can give you the best guidance on how to modify your application time.

    Please keep us posted on what you find out and best of luck as you begin treatment! We are here for you! April, SkinCancer.net, Moderator

    1. Thank You April. That was my thinking also. I have used FU5 in January for 2 to 3 weeks. Just finished on my arms, legs, and chest and am in healing mode, using Acquaphor. Will use on hands @ night w/gloves on, so i do not touch my face.

    2. @susieq21...Just checking in with you to see how healing is going. I hope you have been able to avoid the better part of the discomfort that stage can bring.

      Wishing you all the best! April, SkinCancer.net, Moderator

  2. , I don't know if you have already done it, but here is what I do. I put it on in the morning and night and hope that some seeps in in the morning. At night I put on gloves. One of my docs has me wrap treated areas in Saran Wrap (or any plastic wrap) which I have done on my arms but not my hands because close-fitting exam gloves work. I wouldn't extent the time period without asking!

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