I have just finished two weeks of twice-daily treatment with fluorouracil 5% for sun-damaged skin (no specific actinic keratoses identified) ob my forearms. i have a lot of itching and minor scaliness. My doctor prescribed clobetasol, to be begun after the fluorouracil treatment ended, i.e., today. I am wondering if the anti-inflammatory effects of the clobetasol will reduce the effectiveness of the fluorouracil treatment.