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Mild to Moderate Dysplastic Compound Nevus biopsy result

I am Asian, 29 years old, and I got a mole on my left forehead, the size is 10x9x1mm, and it has been 8-10 years since I found it exist, it indeed doesn't changed much (probably slightly bigger, not that much).

But for peace of mind, I went to biopsy and it is the report:

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CLINICAL HISTORY:

Irregular, pigmented macule.

CLINICAL DIAGNOSIS:

Neoplasm of uncertain behavior. D48.5. R/O atypical nevus.

GROSS DESCRIPTION:

10x9x1 mm oval (black)

MICROSCOPIC:

"Left superior lateral forehead: Sections show a somewhat broad and disordered proliferation of melanocytes disposed

singly but predominantly in nests along the dermal-epidermal junction. Junctional melanocytes display mild to moderate atypia, are focally disposed in nests that bridge adjacent rete ridges, and extend laterally beyond the intradermal component. Pagetoid extension is not observed, as highlighted by a Melan-A immunoperoxidase stain (with an appropriately staining external control). Within the dermis there are melanocytes disposed singly and in nests. Some of the papillary dermal melanocytes display mild nuclear variability. The cells show a tendency to mature and disperse with descent. There is capillary vascular ectasia and mild inflammation. The process closely extends to the peripheral margin and focally involves the base of the specimen."

IMPRESSION:

LEFT SUPERIOR LATERAL FOREHEAD: COMPOUND NEVUS WITH MILD TO MODERATE

DYSPLASIA, SEE COMMENT.

COMMENT:

Some of the atypical findings may be site-related. Appropriate clinical follow up is advised with re-excision should this lesion persist or recur.

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I will go to have re-excision for peace of mind.

There's so many different aspect on the internet which describe dysplastic nevus, so I have few question follow up with that...

1) does dysplastic nevus means benign?

2) can dermatopathologist ensure / validate no more melanocytes left on my head after re-excision?

3) would this be recur even after re-excision?

4) will I still remain in high risk of skin-cancer even after re-excision?

  1. Hi - thank you so much for sharing your biopsy results with us. I'm sorry to hear you're going through this, but it seems like you are being proactive and asking all of the right questions. When are you going for a re-excision? Unfortunately, we cannot provide medical advice for your own safety, but I think the questions you've outlined above would be fantastic to ask your doctor or surgeon. In the meantime, I did want to share some articles we have on dysplastic nevus that may be helpful to read, if you haven't already: https://skincancer.net/life-with-skin-cancer/facts-dysplastic-nevus-syndrome, https://skincancer.net/life-with-skin-cancer/recurrence-rates-risks. I hope these links are helpful! Wishing you the best with re-excision and please keep me posted on how you're doing! -Alexa (SkinCancer.net moderator)

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