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Medication and skin cancer link

I have recurring skin cancers and have been recently researching some of the medications I am taking because I’ve been switched from propranolol to candesartan for my migraines. I have found quite a lot of worrying information regarding link with medications and skin cancer.
Source: ECRjournal.com
“The association between diuretics, in particular thiazides, and skin cancer is supported by the fact that they are photosensitisers, causing direct damage to DNA and chronic subclinical skin inflammation. However, photosensitivity is also a common reaction to many widely used drugs, such as antibiotics, non-steroidal anti-inflammatory drugs and statins, which are often used in the polypharmacy of hypertensive patients.29,30 Self-reported consumption of diuretics, including thiazides, was associated with an increased risk of basal cell carcinoma (BCC) in a nationwide US population-based cohort study”.
This is just some of the info I’ve found. I also didn’t realise how my cymbalata has increased the photosensitivity of my skin so much , but it all makes sense now , why in the past my skin seemed to turn red even in 5 mins of sun.
I have spoken to a pharmacist about this and they are reluctant to discuss this apart from saying that it is often the binding ingredients that cause the problems.I am looking to getting more clinical access into double blind research regarding this. I know that sometimes medicatiion is withdrawn (as in Zantac) when a problem is found. I suppose it is very difficult to prove with skin cancer because of historical sun damage but nevertheless if my medications cause my skin to be more photosensitive then I am worried. Thankfully I do not take any diuretics.

  1. Very interesting. I appreciate you sharing this information. I think I will ask my doctor and pharmacist about this.

    1. Thank you for making us aware of these potential issues. Please keep us updated as you continue your research. Always interested in this. Scott skincancer.net moderator

      1. There is a trade off to everything, and, as you said, it is hard to prove what exactly is causing our skin cancer, due to past exposure, the changing environment (i.e. climate change), current practices (in my case for example forgetting to reapply sunscreen), and who know what other factors. What does your doctor say? Have you talked to your dermatologist about possibly taking niacinamide? Research has shown that it can cut down on skin cancer occurrence. Of course, there could be side effects to it too. Good luck and keep us updated! Ronni (skincancer.net moderator)

        1. I’ve read your very helpful and comprehensive link re. Niacinamide. Thanks, I feel informed looking for the appropriate supplement now.

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